Leona D Samson Selected Research

3-methyladenine-DNA glycosylase

11/2014	Aag-initiated base excision repair promotes ischemia reperfusion injury in liver, brain, and kidney.
3/2010	Frameshift mutagenesis and microsatellite instability induced by human alkyladenine DNA glycosylase.
1/2009	Aag-initiated base excision repair drives alkylation-induced retinal degeneration in mice.
12/2003	The adaptive imbalance in base excision-repair enzymes generates microsatellite instability in chronic inflammation.

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Leona D Samson Research Topics

Disease

25	Neoplasms (Cancer) 01/2022 - 10/2005
10	Inflammation (Inflammations) 12/2019 - 12/2003
8	Carcinogenesis 01/2019 - 07/2008
4	Necrosis 12/2019 - 05/2013
3	Retinal Degeneration 12/2019 - 01/2009
3	Colonic Neoplasms (Colon Cancer) 05/2016 - 12/2003
2	Glioblastoma (Glioblastoma Multiforme) 01/2017 - 08/2015
2	Microsatellite Instability 03/2010 - 12/2003
1	Gliosis 12/2019
1	Genomic Instability 11/2019
1	Colorectal Neoplasms (Colorectal Cancer) 01/2019
1	Hypoproteinemia 07/2016
1	Kidney Diseases (Kidney Disease) 07/2016
1	Renal Insufficiency (Renal Failure) 07/2016
1	Proteinuria 07/2016
1	Ischemia 11/2014
1	Disease Susceptibility (Diathesis) 07/2014
1	Mitochondrial Diseases (Mitochondrial Disease) 05/2013
1	Colitis 07/2012
1	Neurodegenerative Diseases (Neurodegenerative Disease) 01/2011
1	Alzheimer Disease (Alzheimer's Disease) 01/2011
1	Tauopathies 01/2011
1	Inflammatory Bowel Diseases (Inflammatory Bowel Disease) 07/2008
1	Chronic Disease (Chronic Diseases) 11/2007
1	Breast Neoplasms (Breast Cancer) 07/2006
1	Melanoma (Melanoma, Malignant) 05/2004
1	Skin Neoplasms (Skin Cancer) 05/2004
1	Squamous Cell Carcinoma (Epidermoid Carcinoma) 05/2004
1	Basal Cell Carcinoma (Rodent Ulcer) 05/2004
1	Ulcerative Colitis 12/2003
1	Hypersensitivity (Allergy) 10/2003

Drug/Important Bio-Agent (IBA)

16	DNA (Deoxyribonucleic Acid)IBA 01/2022 - 05/2004
10	Alkylating AgentsIBA 01/2022 - 01/2009
8	Proteins (Proteins, Gene)FDA Link 01/2022 - 08/2007
6	NitrogenIBA 01/2018 - 07/2008
5	DNA Glycosylases (DNA Glycosylase)IBA 12/2019 - 12/2010
5	Oxygen (Dioxygen)IBA 01/2018 - 07/2008
4	MethyltransferasesIBA 01/2019 - 07/2006
4	O-(6)-methylguanineIBA 01/2019 - 07/2006
4	3-methyladenine-DNA glycosylaseIBA 11/2014 - 12/2003
2	CytokinesIBA 12/2019 - 07/2008
2	MutagensIBA 01/2019 - 01/2011
2	ArsenicIBA 01/2019 - 11/2007
2	Temozolomide (Temodar)FDA LinkGeneric 01/2017 - 08/2015
2	Pharmaceutical PreparationsIBA 01/2017 - 08/2015
2	Methyl MethanesulfonateIBA 07/2016 - 10/2003
2	AzoxymethaneIBA 05/2016 - 12/2010
2	Poly(ADP-ribose) Polymerases (Poly ADP Ribose Polymerase)IBA 11/2014 - 05/2013
2	Biological ProductsIBA 07/2014 - 09/2008
2	EnzymesIBA 07/2012 - 12/2003
1	NitrosaminesIBA 01/2021
1	8-hydroxyguanosineIBA 12/2019
1	Phosphotransferases (Kinase)IBA 12/2019
1	ChemokinesIBA 12/2019
1	HMGB1 Protein (HMG1)IBA 12/2019
1	ChromatinIBA 11/2019
1	colibactinIBA 01/2019
1	Biomarkers (Surrogate Marker)IBA 01/2019
1	Immune Checkpoint InhibitorsIBA 01/2018
1	Estradiol (Delestrogen)FDA LinkGeneric 09/2017
1	Poly(ADP-ribose) Polymerase InhibitorsIBA 09/2017
1	Urea (Carbamide)FDA LinkGeneric 07/2016
1	CreatinineIBA 07/2016
1	Dextrans (Dextran)FDA Link 05/2016
1	sodium sulfate (sodium bisulfate)FDA LinkGeneric 05/2016
1	Proliferating Cell Nuclear Antigen (PCNA)IBA 11/2015
1	Messenger RNA (mRNA)IBA 08/2015
1	PolymersIBA 11/2014
1	Adenosine Triphosphate (ATP)IBA 05/2013
1	NAD (NADH)IBA 05/2013
1	Reactive Oxygen Species (Oxygen Radicals)IBA 05/2013
1	DioxygenasesIBA 07/2012
1	DNA Repair EnzymesIBA 07/2012
1	Adenine FDA LinkGeneric 07/2012
1	Vinyl Chloride (Chloroethylene)IBA 01/2012
1	GlucosidesIBA 01/2011
1	CycasinIBA 01/2011
1	A-Form DNA (A-DNA)IBA 01/2011
1	Neurofibromin 1 (Neurofibromin)IBA 09/2008
1	Cyclophosphamide (Cytoxan)FDA LinkGeneric 09/2008
1	Drinking WaterIBA 07/2008
1	Dextran SulfateIBA 07/2008
1	MetalsIBA 11/2007
1	NF-kappa B (NF-kB)IBA 11/2007
1	Estrogens (Estrogen)FDA Link 07/2006
1	Estrogen ReceptorsIBA 07/2006
1	AlkB EnzymesIBA 10/2005
1	1,2- di- (4- sulfamidophenyl)- 4- butylpyrazolidine- 3,5- dione (DSB)IBA 05/2004
1	Free RadicalsIBA 12/2003
1	EndonucleasesIBA 12/2003

Therapy/Procedure

4	Therapeutics 01/2019 - 10/2012
3	Drug Therapy (Chemotherapy) 01/2022 - 12/2010